After a six-month battle with tumors on her brain and spine, Villegas' daughter, Mia, passed away on July 26, 2020. She was 22 months old. For weeks after her passing, players, staff and volunteers at events across all Tours wore rainbow ribbons in memory of Mia. Along with wife Maria, Villegas launched Mia's Miracles, an initiative under the Camilo Villegas Foundation, with the mission to provide help to children and families facing challenging circumstances.

Is passionate about bike riding and has what he calls "obsessive cycling disorder."

Has tattoos on his wrist with inspirational sayings. On the right, "attitude" and on the left, "positive energy."